Colleges
Apostolos Tsiachristas
PhD
Associate Professor in Health Economics
- Lead of Oxford Mental Health Economic and Policy (OMHEP) group
- Associate Professor in Nuffield Department of Primary Care Health Sciences, University of Oxford
Prioritisation and incentivisation in mental health care
Apostolos is an Associate Professor in Health Economics at University of Oxford, where he is leading a programme of research that focuses mainly on the economic evaluation of new models of care, particularly for people with mental health and multi-morbidity, and financial incentives in healthcare. He is also is leading the Oxford Mental Health Economics and Policy (OMHEP) group. Apostolos has worked in several experimental and observational studies across a wide range of services for prevention, diagnosis and treatment in several clinical areas but mainly in mental health. He has raised more than £5 million in research funding for health economics mainly by British organizations (e.g. NIHR, Welcome Trust, Health Foundation, and local health authorities) and the European Commission.
He also holds a honorary contract with the Office for Health Improvement and Disparities (UK GOV) where he advises on matters related to mental health economics and policy, and he acts as a scientific advisor to the World Health Organization on topics related to health financing.
Apostolos has developed international reputation in these areas of research through more than 80 scientific publications and book chapters as well as numerous presentations at prestigious conferences. As a recognised expert in payments and financing of chronic care, he has given invited talks, keynote speeches, and advice to several governments (e.g. UK, Ireland, The Netherlands, Belgium, Estonia, and Australia) as well as to national (e.g. Royal Society of Medicine in London, NHS England, Diabetes UK, and Austrian Platform for Personalized Medicine) and international organisations (e.g. European Commission and World Health Organization). Apostolos’ work has received substantial attention in (social) media outlets and has influenced health policy and clinical guidelines (e.g. the Early Intervention in Psychosis Programme of NHS England, and the Cervical Cancer Screening Programme of Public Health England).
Apostolos has co-developed, coordinated, and taught in numerous undergraduate, postgraduate, and professional courses in health economics in Oxford and Rotterdam and has supervised several postgraduate students. Apostolos is an editor of four international journals and member of several scientific committees as well as a Research Fellow at Oxford's Green Templeton College.
Key publications
The early impact of the COVID-19 pandemic on patients with severe mental illness: An interrupted time-series study in South-East England.
Journal article
Penington E. et al, (2022), Eur Psychiatry, 65
Appraisal of patient-level health economic models of severe mental illness: systematic review.
Journal article
Altunkaya J. et al, (2021), Br J Psychiatry, 220, 1 - 12
Survival and community care use by care home residents in England: does mental health matter?
Journal article
Tsiachristas A. et al, (2021), Ageing and Society, 1 - 15
How does reorganisation in child and adolescent mental health services affect access to services? An observational study of two services in England.
Journal article
Fazel M. et al, (2021), PLoS One, 16
Incidence and general hospital costs of self-harm across England: estimates based on the multicentre study of self-harm.
Journal article
Tsiachristas A. et al, (2020), Epidemiol Psychiatr Sci, 29
The economic impact of violence perpetration in severe mental illness: a retrospective, prevalence-based analysis in England and Wales.
Journal article
Senior M. et al, (2020), Lancet Public Health, 5, e99 - e106
Impact of transforming mental health services for young people in England on patient access, resource use and health: a quasi-experimental study.
Journal article
Rocks S. et al, (2020), BMJ Open, 10
Economic impact of early intervention in psychosis services: results from a longitudinal retrospective controlled study in England.
Journal article
Tsiachristas A. et al, (2016), BMJ Open, 6
B-vitamins are potentially a cost-effective population health strategy to tackle dementia: Too good to be true?
Journal article
Tsiachristas A. and Smith AD., (2016), Alzheimers Dement (N Y), 2, 156 - 161
Exploring payment schemes used to promote integrated chronic care in Europe.
Journal article
Tsiachristas A. et al, (2013), Health Policy, 113, 296 - 304
Recent publications
Research priorities for data science and artificial intelligence in global health: an international consensus exercise.
Journal article
Song P. et al, (2026), Lancet Glob Health, 14, e455 - e465
Towards a Multi-sectoral Approach to Population Health: A Scoping Review of Cross-sectoral Evaluations of Health Interventions.
Journal article
Koleva-Kolarova R. et al, (2026), Appl Health Econ Health Policy
Correction: Preferences for multi-cancer tests (MCTs) in primary care: discrete choice experiments of general practitioners and the general public in England.
Journal article
Buckell J. et al, (2026), Br J Cancer, 134, 175 - 176
Value-Based Commissioning of Mental Health Services in England: A Feasibility Study Using Multicriteria Decision Analysis.
Journal article
Gongora-Salazar P. et al, (2025), Value Health, 28, 1802 - 1810
Identifying the Presence and Timing of Self-harm in Electronic Mental Health Records Using Privacy-Preserving Local Language Models: Methodological Study (Preprint)
Journal article
Kormilitzin A. et al, (2025), JMIR Mental Health
Privacy-preserving local language models accurately identify the presence and timing of self-harm in electronic mental health records (Preprint)
Preprint
Kormilitzin A. et al, (2025)
Decision Analytic Models to Assess the Cost-Effectiveness of Prevention, Detection, and Treatment in Multiple Long-Term Conditions: A Scoping Review.
Journal article
Tahsina T. et al, (2025), Value Health
Safeguarding children and supporting families: A longitudinal programme evaluation using routine data.
Journal article
Buivydaite R. et al, (2025), Child Abuse Negl, 169
Privacy-preserving local language models accurately identify the presence and timing of self-harm in electronic mental health records
Preprint
Kormilitzin A. et al, (2025)
Cost-effectiveness of ten commonly used antipsychotics in first-episode schizophrenia in the UK: economic evaluation based on a de novo discrete event simulation model.
Journal article
Zhou J. et al, (2025), Br J Psychiatry, 227, 545 - 552
Preferences for multi-cancer tests (MCTs) in primary care: discrete choice experiments of general practitioners and the general public in England.
Journal article
Buckell J. et al, (2025), Br J Cancer, 133, 394 - 403
Variation in duration of repeat prescriptions: a primary care cohort study in England.
Journal article
MacKenna B. et al, (2025), Br J Gen Pract, 75, e448 - e456
Critical components of 'Early Intervention in Psychosis': national retrospective cohort study.
Journal article
Williams R. et al, (2025), Br J Psychiatry, 1 - 9
Cost-effectiveness of a novel AI technology to quantify coronary inflammation and cardiovascular risk in patients undergoing routine coronary computed tomography angiography.
Journal article
Tsiachristas A. et al, (2025), Eur Heart J Qual Care Clin Outcomes, 11, 434 - 444
Risk of bias in routine mental health outcome data: the case of Health of the Nation Outcome Scales.
Journal article
Penington E. et al, (2025), BMJ Ment Health, 28
Long-term outcomes after stress echocardiography in real-world practice: a 5-year follow-up of the UK EVAREST study.
Journal article
Woodward W. et al, (2025), Eur Heart J Cardiovasc Imaging, 26, 187 - 196
Novel AI technology to quantify coronary inflammation and cardiovascular risk with routine coronary computed tomography angiography: A cost-effectiveness analysis
Journal article
Chan K. et al, (2025), ATHEROSCLEROSIS, 407
Risk of bias in routine mental health outcome data: the case of Health of the Nation Outcome Scales
Journal article
Penington E. et al, (2025), BMJ mental health, 28
Incorporating Complexity and System Dynamics into Economic Modelling for Mental Health Policy and Planning.
Journal article
Crosland P. et al, (2024), Pharmacoeconomics, 42, 1301 - 1315
Unravelling Elements of Value of Healthcare and Assessing their Importance Using Evidence from Two Discrete-Choice Experiments in England.
Journal article
Gongora-Salazar P. et al, (2024), Pharmacoeconomics, 42, 1145 - 1159
Self-poisoning with paracetamol in England: short report of characteristics of individuals and their overdoses according to source of tablets.
Journal article
Brand F. et al, (2024), BJPsych Open, 10
Identification of the Risk Factors for Complex-Multiple Long-term Conditions (C-MLTC): A Scoping Review
Preprint
Heneghan CJ. et al, (2024)
A cloud-based medical device for predicting cardiac risk in suspected coronary artery disease: a rapid review and conceptual economic model.
Journal article
Westwood M. et al, (2024), Health Technol Assess, 28, 1 - 105
Inflammatory risk and cardiovascular events in patients without obstructive coronary artery disease: the ORFAN multicentre, longitudinal cohort study.
Journal article
Chan K. et al, (2024), Lancet, 403, 2606 - 2618
Variation in prescription duration for long term conditions: a cohort study in English NHS primary care using OpenPrescribing
Preprint
MacKenna B. et al, (2024)
Rationing in an Era of Multiple Tight Constraints: Is Cost-Utility Analysis Still Fit for Purpose?
Journal article
Dakin H. and Tsiachristas A., (2024), Appl Health Econ Health Policy, 22, 315 - 329
Cost-effectiveness of therapist-assisted internet-delivered psychological therapies for PTSD differing in trauma focus in England: an economic evaluation based on the STOP-PTSD trial.
Journal article
Penington E. et al, (2024), Lancet Psychiatry, 11, 339 - 347
The impact of the COVID-19 pandemic on children and adolescent mental health in-patient service use in England: interrupted time-series analysis of national patient records.
Journal article
Tsiachristas A. et al, (2024), BJPsych Open, 10
Assessing the relationship between coverage of essential health services and poverty levels in low- and middle-income countries.
Journal article
Guerra S. et al, (2024), Health Policy Plan, 39, 156 - 167
The impact of a new approach to family safeguarding in social care: Initial findings from an analysis of routine data
Journal article
Irving D. et al, (2024), Child and Family Social Work
A protocol for mobilising novel finance models for collaborative health promotion and disease prevention initiatives: taking a smart capacitating investment approach in the Invest4Health project.
Journal article
Lane J. et al, (2024), Front Public Health, 12
Challenges and solutions to system-wide use of precision oncology as the standard of care paradigm.
Journal article
Lajmi N. et al, (2024), Camb Prism Precis Med, 2
ARE SOCIAL IMPACT BONDS THE ANSWER TO LIMITED HEALTHCARE RESOURCES FOR IMPROVING HEALTH PROMOTION AND DISEASE PREVENTION?
Conference paper
Planko S. et al, (2024), VALUE IN HEALTH, 27, S325 - S325
Integrated care in a Beveridge system: experiences from England and Denmark.
Journal article
Tsiachristas A. et al, (2023), Health Econ Policy Law, 18, 345 - 361
Predictors of positive patient-reported outcomes from 'Early Intervention in Psychosis': a national cross-sectional study.
Journal article
Williams R. et al, (2023), BMJ Ment Health, 26
Therapist-assisted online psychological therapies differing in trauma focus for post-traumatic stress disorder (STOP-PTSD): a UK-based, single-blind, randomised controlled trial.
Journal article
Ehlers A. et al, (2023), Lancet Psychiatry, 10, 608 - 622
Cost-effectiveness of extended DPYD testing before fluoropyrimidine chemotherapy in metastatic breast cancer in the UK.
Journal article
Koleva-Kolarova R. et al, (2023), Per Med, 20, 339 - 355
Cost-effectiveness and budget impact analysis of screening strategies for maturity-onset diabetes of the young in three European countries.
Journal article
Szilberhorn L. et al, (2023), Per Med, 20, 387 - 399
Cost-effectiveness of genetic-based screening strategies for maturity-onset diabetes of the young.
Journal article
Kovács G. et al, (2023), Per Med, 20, 375 - 385
Financial incentives to promote personalized medicine in Europe: an overview and guidance for implementation.
Journal article
Koleva-Kolarova R. et al, (2023), Per Med, 20, 305 - 319
Lessons learned from the application of the HEcoPerMed guidance to three modeling case studies.
Journal article
Nagy B. et al, (2023), Per Med, 20, 401 - 411
Budget impact and transferability of cost-effectiveness of DPYD testing in metastatic breast cancer in three health systems.
Journal article
Koleva-Kolarova R. et al, (2023), Per Med, 20, 357 - 374
The impact of the COVID-19 pandemic on children and adolescent mental health inpatient service use in England: An interrupted time-series analysis of national patient records
Journal article
Tsiachristas A. et al, (2023), European psychiatry : the journal of the Association of European Psychiatrists, 66, S340 - S341
Real world hospital costs following stress echocardiography in the UK: a costing study from the EVAREST/BSE-NSTEP multi-entre study.
Journal article
Johnson CL. et al, (2023), Echo Res Pract, 10
The Use of Multicriteria Decision Analysis to Support Decision Making in Healthcare: An Updated Systematic Literature Review.
Journal article
Gongora-Salazar P. et al, (2023), Value Health, 26, 780 - 790
Cost-Effectiveness Analysis of Treating Patients With NTRK-Positive Cancer With the Histology-Independent Therapy Entrectinib.
Journal article
Huygens S. et al, (2023), Value Health, 26, 193 - 203
Predictors of positive outcomes from 'Early Intervention in Psychosis': protocol for a national retrospective cohort study.
Journal article
Williams R. et al, (2023), Front Psychiatry, 14
The impact of the COVID-19 pandemic on children and adolescent mental health inpatient service use in England: An interrupted time-series analysis of national patient records
Conference paper
Tsiachristas A. et al, (2023), EUROPEAN PSYCHIATRY, 66, S340 - S341
Cost-effectiveness of implementing a suicide prediction tool (OxMIS) in severe mental illness: Economic modeling study.
Journal article
Botchway S. et al, (2022), Eur Psychiatry, 66
Moving Beyond Quality-Adjusted Life-Years in Elderly Care: How Can Multicriteria Decision Analysis Complement Cost-Effectiveness Analysis in Local-Level Decision Making.
Journal article
Hoedemakers M. et al, (2022), Value Health, 25, 1717 - 1725
The WISDOM self-management intervention: A cost-effectiveness analysis to support the transformation of type 2 diabetes care in England.
Journal article
Singh S. et al, (2022), Diabet Med, 39
Heterogeneity in preferences for outcomes of integrated care for persons with multiple chronic diseases: a latent class analysis of a discrete choice experiment.
Journal article
Hoedemakers M. et al, (2022), Qual Life Res, 31, 2775 - 2789
The Net Benefit of Personalized Medicine: A Systematic Literature Review and Regression Analysis.
Journal article
Vellekoop H. et al, (2022), Value Health, 25, 1428 - 1438
Financing and Reimbursement Models for Personalised Medicine: A Systematic Review to Identify Current Models and Future Options.
Journal article
Koleva-Kolarova R. et al, (2022), Appl Health Econ Health Policy, 20, 501 - 524
The early impact of the COVID-19 pandemic on patients with severe mental illness: An interrupted time-series study in South-East England.
Journal article
Penington E. et al, (2022), Eur Psychiatry, 65
Can upfront DPYD extended variant testing reduce toxicity and associated hospital costs of fluoropyrimidine chemotherapy? A propensity score matched analysis of 2022 UK patients.
Journal article
Tsiachristas A. et al, (2022), BMC Cancer, 22
