Ivan Koychev
PhD MRCPsych
Senior Clinical Researcher
- Clinician Scientist Dementias Platform UK
- Consultant Neuropsychiatrist Oxford University Hospitals NHS Foundation Trust
I am a clinical academic psychiatrist (on the GMC Specialist Register for Old Age and General Adult Psychiatry) with a focus on the development of treatments for neuropsychiatric disorders. My research spans the key components of neuroscience clinical trial methodology: conduct of proof-of-concept (PoC) biomarker-based clinical trials in surrogate populations, testing of repurposed compounds, development of stratification and efficacy biomarkers and creation of infrastructure for large-scale stratified recruitment into neuroscience experimental medicine studies and clinical trials. Clinically, I focus on the assessment and management of patients with neuropsychiatric presentations in acute medical settings.
Recent publications
The Nottingham consensus on dementia risk reduction policy: recommendations from a modified Delphi process.
Journal article
Demnitz-King H. et al, (2026), Nat Rev Neurol, 22, 123 - 135
Cardiovascular Risk as a Moderator of the Relationship Between Plasma Alzheimer Disease Biomarkers and Cognitive Status.
Journal article
Kancheva AK. et al, (2026), J Am Heart Assoc, 15
Digital cognition plus plasma p-Tau217 and Aβ42/40 powerfully predict Alzheimer's progression.
Journal article
Begde A. et al, (2026), Alzheimers Dement (Amst), 18
Relationships between heritable dementia risk factors, cardiovascular risk factors in young adulthood, and midlife neuropsychological outcomes.
Journal article
Koychev I. et al, (2026), J Alzheimers Dis, 109, 757 - 767
