Animal and human evidence implicate the central noradrenergic system in the process of memory modulation for emotional material. Blockade of the beta-adrenergic system in humans has been shown to result in decreased recall and recognition memory performance, relative to placebo, for the emotional elements of a series of slides accompanied by a narrative. Stimulation of the noradrenergic system with yohimbine has also been shown to result in increased recall and recognition performance relative to placebo for the same stimulus materials.

More information
Type

Journal article

Journal

Psychopharmacology (Berl)

Publication Date

01/2002

Volume

159

Pages

311 - 318

Keywords

Adrenergic Uptake Inhibitors, Adult, Analysis of Variance, Blood Pressure, Dose-Response Relationship, Drug, Double-Blind Method, Female, Heart Rate, Humans, Memory, Mental Recall, Morpholines, Norepinephrine, Recognition (Psychology)