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Recently, Canadian, US and European health regulatory agencies issued warnings about an increased risk of stroke and death in elderly patients with dementia receiving atypical antipsychotics. Assessing both randomised and non-randomised evidence, this systematic review found conflicting findings, particularly for risperidone. More research is needed to better inform clinical practice.


Journal article


Mini Rev Med Chem

Publication Date





776 - 783


Aged, Antipsychotic Agents, Cerebrovascular Disorders, Dementia, Humans