Kate Saunders

DPhil MRCPsych FHEA

Associate Professor

Director of Medical Studies
Honorary Consultant Psychiatrist
Oxford Postgraduate Psychiatry Course Organiser
Academic Foundation Lead

Mood instability, Borderline personality disorder, Bipolar disorder

My early research focused on suicidal behaviour, while my doctorate explored psychiatric phenotypes. As part of this work I conducted one of the first studies to distinguish bipolar disorder and borderline personality disorder on the basis of cognitive function and social behaviour. In 2014 I was given a NARSAD Young Investigator award by the Brain and Behaviour Foundation to study whether deficits in social cognition are a valid treatment target in borderline personality disorder. Alongside this, in conjunction with colleagues at the Institute of Biomedical Engineering I set-up, and am the clinical lead for, the AMoSS study, which uses smart-phones and wearable devices e.g. actigraphs, to prospectively explore mood and related behavioural variables in a cohort of bipolar and borderline patients. This has integrated with my current role in the Wellcome Trust funded CONBRIO programme, which focuses on deep and frequent phenotyping of mood instability and the development of new mathematical approaches to the analysis of mood and related data.

I also the course organiser for the Oxford MRCPsych Course.

I am funded by a Wellcome Trust Strategic Award: Collaborative Oxford Network for Bipolar Research to Improve Outcomes (CONBRIO). I was a graduate scholar at Jesus College Oxford and have been awarded the Florence Stoney studentship by the British Federation for Women Graduates.

Key publications

Borderline personality disorder, but not euthymic bipolar disorder, is associated with a failure to sustain reciprocal cooperative behaviour: implications for spectrum models of mood disorders.
Journal article

Saunders KEA. et al, (2015), Psychol Med, 45, 1591 - 1600
Suicidal behaviour in bipolar disorder: understanding the role of affective states.
Journal article

Saunders KEA. and Hawton K., (2015), Bipolar Disord, 17, 24 - 26
Evidence-based guidelines for treating bipolar disorder: Revised third edition recommendations from the British Association for Psychopharmacology.
Journal article

Goodwin GM. et al, (2016), J Psychopharmacol, 30, 495 - 553
Rationale and design of OxLith: a randomised placebo controlled trial exploring the short-term physical and psychological effects of lithium on mood instability
Conference paper

Geddes JR. et al, (2015), BIPOLAR DISORDERS, 17, 110 - 110
Variability in phase and amplitude of diurnal rhythms is related to variation of mood in bipolar and borderline personality disorder
Journal article

Carr O. et al, Scientific Reports

Recent publications

Large-scale roll out of electronic longitudinal mood-monitoring for research in affective disorders: Report from the UK bipolar disorder research network.
Journal article

Gordon-Smith K. et al, (2018), J Affect Disord, 246, 789 - 793
Apps and wearables in the monitoring of mental health disorders.
Journal article

Patel S. and Saunders KE., (2018), Br J Hosp Med (Lond), 79, 672 - 675
Lamotrigine Therapy for Bipolar Depression: Analysis of Self-Reported Patient Data.
Journal article

Nzeyimana A. et al, (2018), JMIR Ment Health, 5
Daily and weekly mood ratings using a remote capture method in high-risk offspring of bipolar parents: Compliance and symptom monitoring.
Journal article

Duffy A. et al, (2018), Bipolar Disord
Group-Personalized Regression Models for Predicting Mental Health Scores From Objective Mobile Phone Data Streams: Observational Study.
Journal article

Palmius N. et al, (2018), J Med Internet Res, 20

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