Neurobiology of Ageing
Founded in 2007
1600+ Publications
800/800 Whitehall Volunteer Scans (1/12/16)
Funded by EU, MRC, NIHR, ARUK, Alzheimer's Society, Parkinson’s UK & Wellcome Trust
Why do some people suffer from depression and memory loss as they age, whereas others stay well for the whole of their lives? We examine the effect of genes and life history on ageing using neuropsychology and neuro-imaging techniques as part of large scale epidemiological and experimental medicine studies.
If mental health fails in older age, a large number of factors may be responsible: we aim to isolate these using a variety of large and small-scale studies that use all possible methods of enquiry, from clinical interviews and medical examination to neuropsychology and brain imaging.We have teamed up with the Whitehall Study at UCL and the Wellcome Centre for Integrative Neuroimaging (WIN) to examine 800 of their volunteers, who have been followed up 2-yearly for the last 25 years (see quote). Whitehall Imaging Oxford is a participant in the EU Horizon 2020 Project Lifebrain
Our focus of interest is on the interaction of genetic, environmental, social and psychological factors that confer risk and resilience on people as they age. We are also interested in enhancing brain plasticity and resilience by means of exercise, transcranial stimulation and pharmacology.
Our imaging, cognitive and psychiatric research aims to investigate emerging evidence of the brain architecture that enables individuals to compensate cognitively and emotionally, particularly with advancing age.
The wider Old Age Psychiatry and Neuroscience of Ageing theme is comprised of six interacting research groups:
Early Adversity & Brain Health Programme and Modifying Dementia Risk, led by Sarah Bauermeister
Heart and Brain Ageing Group, led by Sana Suri
Dementias Platform UK, led by John Gallacher
Translational Neuroimaging, led by Clare Mackay
Translational Neuroscience and Dementia Research, led by Noel Buckley
Neurobiology of Ageing, led by Klaus Ebmeier
Our team
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Sarah Bauermeister
Associate Professor of Cognitive Neuropsychology
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Sophie Behrman
Honorary Clinical Research Fellow
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Noel Buckley
Professor of Neurobiology
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Ann-Marie de Lange
Senior Research Fellow - PI FemiLab Lausanne
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Klaus Ebmeier
Professor (Chair) & Consultant Old Age Psychiatrist
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Jane Fossey
Associate Director of Psychological Services Oxford Health NHS FT
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John Gallacher
Professor of Cognitive Health; Director, Dementias Platform UK; Director, BrainWaves study of adolescent wellbeing and mental health
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Grace Gillis
DPhil Student & Research Coordinator
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Saba Ishrat
DPhil Student in Psychiatry
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Sara Javidnia
Postdoctoral Research Fellow
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Ivan Koychev
Senior Clinical Researcher
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Morgane Kuenzi
Postdoctoral Researcher Blossom Early Adversity & Brain Health Programme, Dementias Platform UK (DPUK)
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Simon Lovestone
Professor of Translational Neuroscience
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Clare Mackay
Professor of Imaging Neuroscience
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Rupert McShane
Associate Professor
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Patrick Pflanz
Postdoctoral Research Assistant Dementias Platform UK (DPUK)
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Raihaan Patel
Postdoctoral Researcher
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Jemma Pitt
DPhil Student
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Vanessa Raymont
Associate Professor, R&D Director Oxford Health NHS Foundation Trust
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Graham Reid
DPhil Student with Dementias Platform UK (DPUK)
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Meggie Smith
RESEARCH ASSISTANT (DATA CURATION)
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Sana Suri
Associate Professor | Alzheimer's Society Research Fellow
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Benjamin Tari
Postdoctoral Research Analyst Dementias Platform UK (DPUK)
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Anya Topiwala
Wellcome Trust CRCD Fellow; Consultant Psychiatrist
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Vyara Valkanova
Honorary Clinical Research Fellow
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Diana Verley
PA & Research Administrator
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Congxiyu Wang
DPhil Student
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Pippa Watson
DPhil Student
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Philip Wilkinson
Honorary Senior Clinical Lecturer
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Enikő Zsoldos
Postdoctoral Researcher
Recent publications
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Journal article
McCracken C. et al, (2024), BMC Medicine, 22
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Preprint
Bhalerao GV. et al, (2024)
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Journal article
Pflanz CP. et al, (2024), Sci Rep, 14
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Journal article
Leonenko G. et al, (2024), Alzheimers Dement
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Journal article
Jensen DEA. et al, (2024), Nat Commun, 15
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Journal article
Howard R. et al, (2024), Alzheimers Dement
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Journal article
Newton C. et al, (2024), Alzheimers Dement
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Journal article
Lai KY. et al, (2024), Nature Cities
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Journal article
Reid G. et al, (2024), Br J Psychiatry, 1 - 7
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Preprint
Hotchkiss L. et al, (2024)